What is CSV?
The least glamorous and most durable data format there is: rows of values separated by commas, readable by every spreadsheet and database ever written. All its subtlety is in quoting - a value with a comma in it has to be wrapped in quotes, and a quote inside that has to be doubled.
What is XLSX?
A modern Excel workbook, which is really a zip full of XML. Unlike a CSV it knows what a number is, holds multiple sheets, and keeps formulas and formatting. It's what people mean when they say 'send me a spreadsheet'.