What is FLAC?
Lossless compression for audio: about half the size of a WAV, with every sample bit-for-bit intact. It's what people archive CDs into and what hi-res download stores sell. If a conversion starts from FLAC, it's starting from a perfect copy.
What is Opus?
The best-sounding lossy codec at low bitrates by a comfortable margin, which is why it carries the audio in nearly every voice and video call you make. Royalty-free, equally good on speech and music, and usually wrapped in an Ogg container. It always runs at 48kHz internally.